For Patients

 

What is conventional in-vitro fertilization?

When you undergo a routine in-vitro fertilization (IVF) or an intra-cytoplasmic sperm injection (ICSI) cycle, your embryos will be kept in an incubator with strictly controlled environment. Conventionally, during incubation, the embryos must be taken out from the incubator periodically to check its development under a microscope. After checking, the embryos must be returned to the incubator as quickly as possible to avoid any potential damages. This procedure is often done daily during the days of culturing, in order to assess the embryo quality and select the best embryo(s) to be transferred.

 

Step 1: ICSI or IVF of the oocyte
Step 2: Conventional technique requires embryo to be taken out from the incubator at certain time-points for assessment.
Step 3: The embryo is viewed under the microscope as quickly as possible in order to avoid potential damages.

 

Time-Lapse Advantages

  1. Provides new information on the embryo development that was not available before.

     

    The Miri TL allows embryologists to view the development of the embryo from fertilization until the day of transfer. Time-Lapse monitoring enables embryologists to see events such as fragmentation, reverse cleavage, cleavage failure, multinucleation and other important parameters in embryo morphokinetics analysis; that are often unseen using conventional methods. Observance of these events can help assess the viability of embryos and their probability to implant and make a healthy baby.

    Miri TL automatically record images of the cultured embryos every 5 minutes without disturbing the environment. Miri TL software is equipped with multiple tools which allows the embryologists to continuously monitor, compare the embryo development and select the most viable embryo for transfer. These evaluations can be done completely without disturbing the environment inside the incubator and allows the embryologist to detect abnormal events that might occur. Accurate – Competent – Safe. 

     

  2. Enables traceability and documentation of the laboratory handling and selection of embryos.

    The images and the videos which are digitally stored can be used by embryologists for documentation, analysis and future references.

What is Miri® TL?

The Miri® TL is a multi-room incubator with a built-in camera and microscope that allows embryologists to view the development of the embryo from fertilization until the day of transfer without any disturbances. This reduces the environmental stress of the embryo, which can lead to improved embryo competences and higher pregnancy rates. 

This technology also allows important events to be observed which helps in assessing the viability of embryos for implantation and make a healthy baby. 

 

How would this benefit me?

  1. Optimal embryo development and better selection means more pregnancies.
    • Miri® TL has a very stable and maximum controlled conditions which provides better culture environment for your embryos.
    • Based on time-lapse imaging, there is no need to take out the embryos from the incubator during assessment, resulting in less disturbance and minimized stressful factors.
    • Miri® TL has six individual chambers which prevents cross contamination during the process.
    • A combination of superior filtering and sterilization of the incubator air before entering the chamber, gives optimal conditions for best possible embryo development.
  2. Eliminate sample mix up.
    • Miri® TL has six separate chambers which allow embryologists to culture just one patient’s embryos in each chamber which minimize the risk of mixing up the samples.
  3. Capture the very beginning of your baby’s life.
    • Since Miri® TL is capable of recording pictures and videos, you can see the very beginning of your future baby’s life.
  4. Documentation and analysis

    • New information can be obtained as basis for better selection to improve pregnancy success.
    • The stored images and videos can be used in cases where more embryo information is desired. It is helpful when there are repeated implantation failure and recurrent miscarriage.
  5. Higher number of viable embryos
    • Embryo development is at optimum. This may result to reduced number of embryos to transfer and minimize the risks of multiple pregnancy.
    • Miri® TL provides the best possible conditions for embryo development which lead to more viable embryos. Some of these embryos can be vitrified or stored in case you planned to have another baby.

 

Please download the Patient Pamphlet Information.

Whether you are a doctor or a patient, you can find all relevant information regarding the advantages of Miri Time-Lapse with this pamphlet information.

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